Title of article
2-Alkyl-1-(2-aryl-1,1-difluoro-2-hydroxyethyl)benzimidazoles: potential angiotensin II receptor antagonists
Author/Authors
Yagupolskii، نويسنده , , Lev M and Fedyuk، نويسنده , , Dmitrij V، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
3
From page
2265
To page
2267
Abstract
2-Alkyl-1-(bromodifluoromethyl)benzimidazoles were synthesized and condensed with aromatic aldehydes to give 2-alkyl-1-(2-aryl-1,1-difluoro-2-hydroxyethyl)-benzimidazoles. A potential nonpeptide antagonist of the angiotensin II receptor with the -CF2CH(OH)-bridge between the heterocyclic nitrogen atom and the biphenyl moiety was synthesized.
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636707
Link To Document