Title of article
Thalidomide metabolites. Part 1: Derivatives of (+)-2-(N-phthalimido)-γ-hydroxyglutamic acid
Author/Authors
Luzzio، نويسنده , , Frederick A. and Mayorov، نويسنده , , Alexander V. and Figg، نويسنده , , William D.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
2275
To page
2278
Abstract
A mild version of the Lemieux–Johnson olefin cleavage followed by a peroxide-mediated dialdehyde oxidation and esterification effected the conversion of 1-acyloxy-4-N-phthalimido-2-cyclopentenyl esters to γ-oxygenated-N-phthalimidoglutamic ester derivatives.
Keywords
amino acids and derivatives , Cleavage reactions , Imides , Osmylation , Oxidation
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636712
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