Title of article
Studies on chemical modification of monensin. Part 7: Synthesis and Ca2+ ion transport activity of 25-carboxylmonensin
Author/Authors
Nagatsu، نويسنده , , Akito and Tanaka، نويسنده , , Rie and Hashimoto، نويسنده , , Masayo and Mizukami، نويسنده , , Hajime and Ogihara، نويسنده , , Yukio and Sakakibara، نويسنده , , Jinsaku Sakakibara، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
2629
To page
2632
Abstract
Ionophore antibiotic monensin (1) was converted to 25-carboxylmonensin (3), which has two carboxyl groups at both ends of the molecule. Ca2+ ion transport activity of 25-carboxylmonensin (3) was evaluated by the CHCl3 liquid membrane method, and the activity was 3.1 times the value of the calcium ionophore, lasalocid A.
Keywords
ion transport activity , Calcium ionophore , monensin , 25-carboxylmonensin
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636934
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