Author/Authors :
Nagatsu، نويسنده , , Akito and Tanaka، نويسنده , , Rie and Hashimoto، نويسنده , , Masayo and Mizukami، نويسنده , , Hajime and Ogihara، نويسنده , , Yukio and Sakakibara، نويسنده , , Jinsaku Sakakibara، نويسنده ,
Abstract :
Ionophore antibiotic monensin (1) was converted to 25-carboxylmonensin (3), which has two carboxyl groups at both ends of the molecule. Ca2+ ion transport activity of 25-carboxylmonensin (3) was evaluated by the CHCl3 liquid membrane method, and the activity was 3.1 times the value of the calcium ionophore, lasalocid A.
Keywords :
ion transport activity , Calcium ionophore , monensin , 25-carboxylmonensin
