Title of article :
A novel asymmetric route to 2-amino-1,2,3,4-tetrahydronaphthalenes
Author/Authors :
Harris، نويسنده , , Michael C.J and Jackson، نويسنده , , Mark and Lennon، نويسنده , , Ian C and Ramsden، نويسنده , , James A and Samuel، نويسنده , , Helen، نويسنده ,
Abstract :
A novel asymmetric route to 2-amino-1,2,3,4-tetrahydronaphthalenes has been demonstrated starting from phthalimidovinylglycinol (PVG). Functionalisation of PVG via Heck reaction, olefin hydrogenation and cyclisation provides the title products.