Author/Authors :
Lashley، نويسنده , , Matthew R and Nantz، نويسنده , , Michael H، نويسنده ,
Abstract :
We describe a general method for elaboration of the ethyl sidechain of tamoxifen and its primary 4-hydroxy metabolite. Novel lipidic tamoxifen and a functionalized B-ring analog were synthesized from a common stilbene oxide intermediate for potential liposomal applications including estrogen receptor targeting.
