Title of article :
Synthesis of 5(20)deoxydocetaxel, a new active docetaxel analogue
Author/Authors :
Dubois، نويسنده , , Joëlle and Thoret، نويسنده , , Sylviane and Guéritte، نويسنده , , Françoise and Guénard، نويسنده , , Daniel، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
5(20)Deoxydocetaxel was prepared from 13-oxo-10-deacetyl baccatin III. This compound is the first docetaxel analogue with a modified D-ring which is as active as paclitaxel on microtubules.
Keywords :
Microtubules , Taxoids , docetaxel , 10-deacetyl baccatin III , Oxetane
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters