Title of article
Rhodium(I)-catalyzed addition of phenols to dienes. A new convergent synthesis of vitamin E
Author/Authors
Bienaymé، نويسنده , , Hugues and Ancel *، نويسنده , , Jean-Erick and Meilland، نويسنده , , Pierre and Simonato، نويسنده , , Jean-Pierre، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
3339
To page
3343
Abstract
A highly convergent and atom-economical synthesis of (dl)-[α]-tocopherol (vitamin E) is proposed, the realization of which was made possible by the discovery of the regioselective Rh(I)-catalyzed arylation of β-springene with trimethylhydroquinone. Other phenolic compounds and 2-substituted-1,3-dienes were shown to undergo this transformation.
Keywords
vitamin E , Homogeneous catalysis , C-alkylation , phenol , Rhodium
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1637360
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