The first, highly efficient synthesis of spacer-armed O-glycans on GlyCAM-1 and PSGL-1: the counter-receptors for L- and P-selectin

A pair of spacer-armed O-glycans containing sulfated/nonsulfated sialyl Lex (sLex) determinant on GlyCAM-1 and PSGL-1, the counter-receptor glycoproteins for L- and P-selectin, were synthesized for the first time in a highly efficient manner employing a simultaneous glycosylation procedure.