Author/Authors :
Wang، نويسنده , , Xin and Rabbat، نويسنده , , Philippe and O’Shea، نويسنده , , Paul and Tillyer، نويسنده , , Richard and Grabowski، نويسنده , , E.J.J and Reider، نويسنده , , Paul J، نويسنده ,
Abstract :
Selective monolithiation of 2,5-dibromopyridine at either the 2-position or the 5-position is reported. Solvent and concentration strongly influence the selectivity. Coordinating solvents and higher concentration favor the 5-position while non-coordinating solvents and lower concentration favor the 2-position.