Author/Authors :
Rühl، نويسنده , , Thomas and Hennig، نويسنده , , Lothar and Hatanaka، نويسنده , , Yasumaru and Burger، نويسنده , , Klaus and Welzel، نويسنده , , Peter، نويسنده ,
Abstract :
A photolabel, a biotin tag, and a moenomycin ligand have been attached orthogonally to the three functional groups of isoserine to provide compound 13 that is to be used in affinity labeling of penicillin binding protein 1b. The urethane group in 13 can be cleaved with n-butylamine in methanol or water.