Author/Authors :
Bigot، نويسنده , , Antony and Bois-Choussy، نويسنده , , Michèle and Zhu، نويسنده , , Jieping، نويسنده ,
Abstract :
An efficient synthesis of K-13, a non competitive inhibitor of ACE I, with an endo biaryl ether bond is described. The key cycloetherification reaction of linear tripeptide 10 gave 17-membered macrocycle in quantitative yield.
