Title of article :
The first direct ammonolysis of 2-thiouracil nucleosides to 2-thiocytosine nucleosides
Author/Authors :
Strekowski، نويسنده , , Lucjan and Abdou، نويسنده , , Ibrahim M and Attia، نويسنده , , Adel M.E and Patterson، نويسنده , , Steven E، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
Sugar-peracetylated 1-(β-d-glucopyranosyl)-, 1-(β-d-galactopyranosyl)-, and 1-(β-d-xylopyranosyl)-6-aryl-5-cyano-2-thiouracils 2–4 and the corresponding 1-pyranosyl-2-(pyranosylthio)pyrimidines 5–7 undergo efficient ammonolysis (NH3/MeOH, 0→23°C, 16 h) to give the corresponding 1-(β-d-pyranosyl)-6-aryl-5-cyano-2-thiocytosines.
Keywords :
6-aryl-5-cyano-2-thiouracils , 1-(?-d-pyranosyl)-2-thiocytosines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
