Title of article :
A new preparation of 2,5-dihydro-1-benzoxepins using Mitsunobu cyclization, and the synthesis of natural radulanins
Author/Authors :
Yamaguchi، نويسنده , , Seiji and Furihata، نويسنده , , Katsunori and Miyazawa، نويسنده , , Masahiro and Yokoyama، نويسنده , , Hajime and Hirai، نويسنده , , Yoshiro، نويسنده ,
Abstract :
Mitsunobu cyclization of o-[4-hydroxy-3-methyl-2(Z)-butenyl]phenol 2a effected selective seven-membered cyclization to give 3-methyl-2,5-dihydro-1-benoxepin 1a. Using this procedure, natural radulanin A and radulanin A methyl ether were synthesized effectively.
