Blazeispirol X and Y, two novel carbon skeletal sterols from the cultured mycelia of the fungus Agaricus blazei

Two novel blazeispirol derivatives, blazeispirol X and Y, have been isolated from the cultured mycelia of Agaricus blazei (Agaricaceae). The structures were elucidated to be (20S,22S,23R,24S)-1 (10→6) abeo-14β,22:22,25-diepoxyergosta-5,7,9,11-tetraene-3α,23-diol and (20S,22S,23R,24S)-14β,22:22,25-diepoxy-9,23-dihydroxyergosta-4,7,11-triene-3,6-dione by comparison of extensive 1D and 2D NMR spectral data with that of blazeispirol A.