Title of article :
Palladium-catalyzed synthesis of stereodefined 3-[(1,1-unsymmetrically disubstituted)methylidene]isobenzofuran-1(3H)-ones and stereodefined 5-[(1,1-unsymmetrically disubstituted)methylidene]furan-2(5H)-ones
Author/Authors :
Rossi، نويسنده , , Renzo and Bellina، نويسنده , , Fabio and Biagetti، نويسنده , , Matteo and Catanese، نويسنده , , Antonella and Mannina، نويسنده , , Luisa، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
Treatment of (hetero)aryl halides with 2-(1-alkynyl)benzoic acids or (Z)-2-en-4-ynoic acids in the presence of K2CO3 and a catalytic amount of Pd(PPh3)4 provides reaction mixtures in which stereodefined 3-[(1,1-unsymetrically disubstituted)methylidene]isobenzofuran-1(3H)-ones and stereodefined 5-[(1,1-unsymmetrically disubstituted)methylidene]furan-2(5H)-ones, respectively, are the major products.
Keywords :
palladium and reactions , Alkynes , furanones , isobenzofuranones
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
