Title of article
The undesirable lability of tert-butyldimethylsilyl ethers under Pd/C-catalyzed hydrogenation conditions and solution of the problem by using a Pd/C(en) catalyst
Author/Authors
Hattori، نويسنده , , Kazuyuki and Sajiki، نويسنده , , Hironao and Hirota *، نويسنده , , Kosaku، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
5711
To page
5714
Abstract
While the frequent and unexpected loss of the TBDMS protective group of a variety of hydroxylic functions was demonstrated under neutral and mild hydrogenation conditions using 10% Pd/C, the undesirable problem was perfectly overcome by using a 10% Pd/C-ethylenediamine complex catalyst.
Keywords
Chemoselective hydrogenation , TBDMS ethers , Desilylation , Pd/C , Pd/C(en)
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1638280
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