Title of article
New route to the synthesis of the illudane skeleton by Michael–Michael-elimination reaction
Author/Authors
Tokuzaki، نويسنده , , Kazuo and Kanemitu، نويسنده , , Yasuhiro and Yoshimitsu، نويسنده , , Takehiko and Nagaoka، نويسنده , , Hiroto، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
5923
To page
5926
Abstract
A new route to the synthesis of an optically active illudane skeleton from (R)-(−)-pantolactone (4) is established. The tricyclic ring system was constructed by Michael–Michael-elimination reaction of the enolate of (3S,5R)-3-(tert-butyldimethylsilyloxy)-5-methoxymethyloxy-1-propionylcyclopentene (10) with ethyl cyclopropylidenacetate (3).
Keywords
Michael reactions , Antitumor compounds , terpenes and terpenoids
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1638326
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