Author/Authors :
Honda، نويسنده , , Toshio and Namiki، نويسنده , , Hidenori and Kudoh، نويسنده , , Mika and Watanabe، نويسنده , , Naofumi and Nagase، نويسنده , , Hiromasa and Mizutani، نويسنده , , Hirotake، نويسنده ,
Abstract :
A formal total synthesis of securinine (1) was achieved by employing an intramolecular Diels–Alder reaction of the enol ester, derived from 2-acetylpyridine and sorbic anhydride, as a key step.
Keywords :
enol ester , Securinine , Diels–Alder reaction , GABAA receptor antagonist
