Title of article
Highly E-selective synthesis of α,β-unsaturated amides from N-2-methoxyphenyl aldimines via lithium ynolates
Author/Authors
Shindo، نويسنده , , Mitsuru and Oya، نويسنده , , Soichiro and Murakami، نويسنده , , Ryoko and Sato، نويسنده , , Yusuke and Shishido، نويسنده , , Kozo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
5947
To page
5950
Abstract
Lithium ynolates reacted with N-2-methoxyphenyl (OMP) aldimines to afford α,β-unsaturated amides in excellent E-selectivity via a retro-Mannich reaction of the 2:1 adducts (β-lactams), followed by cleavage of the β-lactam enolates.
Keywords
Ynolates , Olefination , Amides , imines
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1638331
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