Title of article :
An efficient and extremely mild method for protecting alcohols as 2-tetrahydrofuranyl ethers
Author/Authors :
Sean P and Barks، نويسنده , , Jenny M and Gilbert، نويسنده , , Bruce C and Parsons، نويسنده , , Andrew F and Upeandran، نويسنده , , Bala، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
Reaction of primary or secondary alcohols with BrCCl3 and tetrahydrofuran, usually in the presence of 2,4,6-collidine, leads to the formation of 2-tetrahydrofuranyl ethers in good to excellent yield (56–92%). The reaction mechanism is believed to involve a free-radical chain reaction.
Keywords :
acetals , protecting groups , radicals and radical reactions , Oxygen heterocycles
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
