Title of article :
Facile chelation-controlled reductive opening of methoxybenzylidene acetals with Bu3SnH and MgBr2. Regioselective protection strategy as MPM ethers
Author/Authors :
Zheng، نويسنده , , Bao-Zhong and Yamauchi، نويسنده , , Megumi and Dei، نويسنده , , Hiroo and Kusaka، نويسنده , , Shin-ichi and Matsui، نويسنده , , Katsuya and Yonemitsu، نويسنده , , Osamu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
A mild and efficient regioselective reductive opening of methoxybenzylidene acetals using a combination of Bu3SnH and MgBr2·OEt2, mainly via five-membered chelation intermediates is described. This reaction was applied to synthetic intermediates of myriaporon and tedanolide.
Keywords :
Reductive cleavage , chelation , tri-n-butyltin hydride , regioselection , magnesium bromide , Protecting group , benzylidene acetal
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
