Author/Authors :
Mizuno، نويسنده , , Akira and Kan، نويسنده , , Yukiko and Fukami، نويسنده , , Harukazu and Kamei، نويسنده , , Tomoe and Miyazaki، نويسنده , , Kazuo and Matsuki، نويسنده , , Shinsuke and Oyama، نويسنده , , Yoshiaki، نويسنده ,
Abstract :
Sulfonation of pyrrole and its 1-methyl derivatives with a sulfur trioxide–pyridine complex was found to give 3-sulfonated pyrroles, but not 2-sulfonates as described in textbooks. The replacement of 1-methyl-2-tri-n-butylstannylpyrrole with trimethylsilyl chlorosulfonate, followed by quenching with aq. NaHCO3 also generated sodium 1-methylpyrrole-3-sulfonate, not 2-sulfonate.
Keywords :
Rearrangements , Bicyclic heterocyclic compounds , pyrroles , Sulfonation
