Author/Authors :
Chang، نويسنده , , Leng Chee and Chلvez، نويسنده , , Daniel and Gills، نويسنده , , Joell J and Fong، نويسنده , , Harry H.S and Pezzuto، نويسنده , , John M and Kinghorn، نويسنده , , A.Douglas، نويسنده ,
Abstract :
Three new anthracene derivatives, rubiasins A–C (1–3), were isolated from the combined roots and stems of Rubia cordifolia, and their structures were elucidated by spectroscopic analysis. Their absolute configurations were determined by Mosher ester methodology. A known compound, mollugin (4), was obtained as an active antiproliferative principle by bioassay-monitored fractionation using a human colon cancer (Col2) cell line.
