Title of article :
Li+ and Na+ switch of enantioselectivity in the desymmetrisation of polycyclic bis(phenylsulfonyl)alkenes by chiral alcohols
Author/Authors :
Cossu، نويسنده , , Sergio and De Lucchi *، نويسنده , , Ottorino and Peluso، نويسنده , , Paola and Volpicelli، نويسنده , , Raffaella، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
A complete switch of enantioselectivity is obtained in the desymmetrisation reaction of polycyclic bis(phenylsulfonyl)alkenes by the change of the base from n-BuLi to NaH, thus allowing convenient access to either enantiomer of polycyclic ketones with the same chiral auxiliary.
Keywords :
desymmetrisation , polycyclic ketones , Sulfones , enantiotopic discrimination
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
