Author/Authors :
Imre Schlemminger، نويسنده , , Imre and Janknecht، نويسنده , , Hans-Hermann and Maison، نويسنده , , Wolfgang and Saak، نويسنده , , Wolfgang and Martens، نويسنده , , Jürgen، نويسنده ,
Abstract :
The first synthesis of an enantiomerically and diastereomerically pure 3-thiazoline via modified Asinger reaction using a galactose derived chiral auxiliary is described. The absolute configuration of this heterocyclic imine has been elucidated via X-ray analysis. In addition, the 3-thiazoline has been successfully derivatized under Ugi conditions.
Keywords :
Enantioselection , Asinger reaction , imines , thiazolines
