Title of article
The squalestatins: tricyclic 3,4-β-lactone and 3,4-oxetane systems
Author/Authors
Cox، نويسنده , , Brian and Morley، نويسنده , , Nicolas and Procopiou، نويسنده , , Panayiotis A and Sharratt، نويسنده , , Peter J and Watson، نويسنده , , Nigel S and Wild، نويسنده , , Deborah، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
7547
To page
7550
Abstract
Squalestatin 3,4-β-lactone-4,5-dimethyl ester (8) was reductively ring-opened to yield squalestatin 3-hydroxymethyl-4,5-dimethyl ester (6) using mild reducing conditions (sodium borohydride). Similarly, squalestatin 3,4-oxetane-4,5-dimethyl ester (10) was found to ring-open to 3-iodomethyl squalestatin (15) under the conditions used to cleave the methyl ester functions (lithium iodide/2,4,6-trimethylpyridine).
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1639059
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