Title of article
One-pot synthesis of isoquinoline-5,8-dione derivatives from acylquinones and enamines
Author/Authors
Kobayashi، نويسنده , , Kazuhiro and Takanohashi، نويسنده , , Atsushi and Watanabe، نويسنده , , Shinya and Morikawa، نويسنده , , Osamu and Konishi، نويسنده , , Hisatoshi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
7657
To page
7660
Abstract
A new and facile method for the preparation of isoquinolinequinone derivatives has been developed. Treatment of 2-acyl-1,4-naphthoquinones or 2-acyl-5,6-dimethyl-1,4-benzoquinones with enamines (or imines), followed by addition of aqueous NH3 in MeOH afforded benz[g]isoquinoline-5,10-dione or isoquinoline-5,8-dione derivatives, respectively, in moderate to good yields.
Keywords
enamines , imines , Isoquinolines , Michael reactions , quinones
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1639109
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