Title of article
Stereospecific synthesis of α,ω-cis- and α,ω-trans-disubstituted oxepanes
Author/Authors
Matsumura، نويسنده , , Ryuji and Suzuki، نويسنده , , Toshio J. Sato، نويسنده , , Kohki and Inotsume، نويسنده , , Takashi and Hagiwara، نويسنده , , Hisahiro and Hoshi، نويسنده , , Takashi and Kamat، نويسنده , , Vijayendra P and Ando، نويسنده , , Masayoshi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
7697
To page
7700
Abstract
An efficient and versatile method for the stereospecific construction of α,ω-cis- and α,ω-trans-disubstituted oxepane skeletons is described. Cyclization of the hydroxy epoxides promoted by a (Bu3Sn)2O/Zn(OTf)2 system proceeded via an SN2 process and exo mode selectivity regardless of the configuration of the hydroxyl and the epoxy groups to provide the corresponding oxepanes in excellent yields.
Keywords
epoxides , cyclization , regioselection , oxepanes
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1639132
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