Determination of the cyclodextrin inclusion constant with the constant current coulometric titration method

With fluorometry this paper has proved that α-cyclodextrin (CD) and γ-CD do not form inclusion complexes with procaine, while β-CD and HP-β-CD do. Their molar ratios are demonstrated both 1:1 with the equimolar variation method. The constant current coulometric titration method (CCCT) is first proposed and applied in the determination of the CD inclusion constant. To compare with this method, the fluorescence experiment has been done with the satisfactory results.