Title of article
Synthesis of the optically active bicyclo[4.3.0]nonane derivative, regarded as the CD ring moiety of 12-oxygenated steroids
Author/Authors
Mitome، نويسنده , , Hidemichi and Miyaoka، نويسنده , , Hiroaki S. Yamada، نويسنده , , Yasuji، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
8107
To page
8110
Abstract
The optically active bicyclo[4.3.0]nonane derivative, considered to be the CD ring moiety of 12-oxygenated steroids was synthesized in the present study, which involved stereo-controlled formation of bicyclo[2.2.2]octane derivative by sequential Michael reaction, formation of tricyclo[5.2.2.02,6]undecane derivative by intramolecular pinacol coupling reaction and the CC bond cleavage by retro-aldol reaction.
Keywords
Michael reactions , bicyclic aliphatic compounds , steroids and sterols
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1639343
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