Title of article
Facile synthesis of l-Dopa tert-butyl ester by catalytic enantioselective phase-transfer alkylation
Author/Authors
Ooi، نويسنده , , Takashi and Kameda، نويسنده , , Minoru and Tannai، نويسنده , , Hidenori and Maruoka، نويسنده , , Keiji، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
8339
To page
8342
Abstract
Facile asymmetric synthesis of l-Dopa and related amino acid esters has been achieved by phase-transfer catalysis of the rationally designed C2-symmetric chiral quaternary ammonium salts 1. The ‘scale-up’ experiment performed with 5.00 g of tert-butyl glycinate-benzophenone Schiff base (2) represents the practical aspect of our approach.
Keywords
chiral phase-transfer catalysis , l-Dopa esters , Alkylation , glycine derivatives
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1639499
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