Title of article
Practical synthesis of a new analytical construct: thiopyrimidine safety-catch linker for facile monitoring of solid-phase chemistry
Author/Authors
Lorthioir، نويسنده , , Olivier and McKeown، نويسنده , , Stephen C. and Parr، نويسنده , , Nigel J. and Washington، نويسنده , , Melanie and Watson، نويسنده , , Stephen P.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
8609
To page
8613
Abstract
We report here a new analytical construct based on a thiopyrimidine safety-catch linker. This construct adds to the existing portfolio of linkers available for facile monitoring of reactions conducted on solid support. A practical solution phase synthesis of the precursor is described, together with the proof of concept and cleavage protocols.
Keywords
analytical construct , safety-catch , Pyrimidine , solid-phase synthesis , mass spectrometry
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1639693
Link To Document