Title of article
A short and efficient synthesis of unnatural (R)-nicotine
Author/Authors
Girard، نويسنده , , Sandrine and Robins، نويسنده , , Richard J and Villiéras، نويسنده , , Jean and Lebreton، نويسنده , , Jacques، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
9245
To page
9249
Abstract
A short and efficient synthesis of unnatural (R)-nicotine is described, in which the key step is an intramolecular hydroboration–cycloalkylation of an azido-olefin intermediate. The synthesis is achieved in only four steps, with an overall yield of 51% (or in six steps with an overall yield of 65%).
Keywords
asymmetric synthesis , Alkaloids , allylation , boron and compounds , Azides
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1640121
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