Title of article
In pursuit of an anticancer vaccine: a monomolecular construct containing multiple carbohydrate antigens
Author/Authors
Williams، نويسنده , , Lawrence J and Harris، نويسنده , , Christina R and Glunz، نويسنده , , Peter W and Danishefsky، نويسنده , , Samuel J، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
9505
To page
9508
Abstract
The synthesis of a new type of anti-cancer vaccine candidate is presented. This compound contains the TF, Ley, and Tn tumor antigens clustered in a monomolecular array. In addition to being a realistic mimic of ‘micro-heterogeneous’ mucins, this class of vaccine may trigger a multifaceted immune response convergent on a particular cancer type.
Keywords
carbohydrates , Synthesis , anti-cancer vaccines , Peptides , tumor-associated carbohydrate antigens
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1640298
Link To Document