Title of article
2,5-Anhydro sugar diacid and 2,5-anhydro sugar diamine based C2 symmetric peptidomimetics as potential HIV-1 protease inhibitors
Author/Authors
Chakraborty، نويسنده , , T.K. and Ghosh، نويسنده , , Subhash and Ramana Rao، نويسنده , , M.H.V and Kunwar، نويسنده , , A.C. and Cho، نويسنده , , Md. Delwar H. and Ghosh، نويسنده , , A.K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
10121
To page
10125
Abstract
Conformationally constrained molecular frameworks of the 2,5-anhydro sugar diacid (9) and 2,5-anhydro sugar diamines (10, 11) were used to construct architecturally beautiful novel C2 symmetric peptidomimetics 1–8. Although none of these compounds showed any significant HIV-1 protease inhibitory activity, further refinements in design may lead to protease inhibitors based on these rigid carbohydrate-derived scaffolds.
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1640703
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