Title of article
Simultaneous reduction of the nitro group and the azide group in o-nitrophenylazide induced by the TiCl4/Sm system: a novel synthesis of 2,3-dihydro-1H-1,5-benzodiazepines
Author/Authors
Zhong، نويسنده , , Weihui and Zhang، نويسنده , , Yongmin and Chen، نويسنده , , Xiaoyuan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
73
To page
75
Abstract
o-Nitrophenylazide was treated with the low-valent titanium reagent derived from the TiCl4/Sm system to produce the intermediate 2 in situ, which was a ‘living’ double-anion and reacted readily with ketones containing active methyl or methylene groups to afford 2,3-dihydro-1H-1,5-benzodiazepines in moderate to high yields under mild and neutral conditions.
Keywords
Samarium , nitro group , Titanium tetrachloride , 2 , 3-dihydro-1H-1 , 5-benzodiazepine , Azide , reductive cyclization
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1640909
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