Author/Authors :
Bailey، نويسنده , , Patrick D and Cochrane، نويسنده , , Philip J and Lorenz، نويسنده , , Katrin and Collier، نويسنده , , Ian D and Pearson، نويسنده , , David P.J and Rosair، نويسنده , , Georgina M، نويسنده ,
Abstract :
Using the kinetically controlled Pictet–Spengler reaction, we have developed a three-step, diastereoselective and enantiospecific synthesis of the natural product demethoxy-fumitremorgin C in 21% overall yield.
Keywords :
Alkaloids , indoles , Pictet–Spengler , Anti-tumour