Title of article :
Suppression of double bond isomerisation in intramolecular Heck reactions using supercritical carbon dioxide
Author/Authors :
Shezad، نويسنده , , Najam and Clifford، نويسنده , , Anthony A and Rayner، نويسنده , , Christopher M، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
The modified reagent system [Pd(OCOCF3)2/P(2-furyl)3/EtNiPr2] gives enhanced conversions compared with standard conditions [Pd(OAc)2/PPh3/NEt3] for intramolecular Heck cyclisations, and when used in scCO2 results in the suppression of double bond isomerisation to minimal levels, which is otherwise a serious competing side reaction in conventional solvents.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
