• Title of article

    Enone structure as a probe to Lewis acid carbonyl binding in copper-catalysed asymmetric conjugate addition

  • Author/Authors

    Bِrner، نويسنده , , Christoph and Kِnig، نويسنده , , Wilfried A and Woodward، نويسنده , , Simon، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    327
  • To page
    329
  • Abstract
    Systematic changes in the substitution pattern of linear enones (R1COCHCHR2) helps identify the reactive conformation (s-trans versus s-cis) of the enone in copper-catalysed asymmetric 1,4-ZnEt2 addition. Pointers to the binding mode of the Lewis Acid (syn or anti to the ‘ene’ function) are also gathered. Enantioselectivities of up to 79% have been realised in these reactions.
  • Keywords
    Mechanisms , Thioethers , zinc and compounds , enones
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1641110

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1641110