Title of article
Diastereoselective reduction of N-phthaloyl α-amino ketones: synthesis of syn-3-amino-1,2-diol derivatives
Author/Authors
Sengupta، نويسنده , , Saumitra and Sen Sarma، نويسنده , , Debarati، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
485
To page
487
Abstract
LiAlH(OBu-t)3 reduction of the chiral-pool derived N-phthaloyl α-amino-α′-acetoxy ketones has led to a facile diastereoselective synthesis of syn-3-amino-1,2-diols (>75% de).
Keywords
?-amino diazoketones , Lithium tri-t-butoxyaluminium hydride , syn-reduction , syn-amino diols
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1641239
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