Title of article :
The synthesis of potentially selective inhibitors of dihydroorotate dehydrogenase. The utilization of chemoselective Suzuki cross-coupling reactions in a parallel synthesis
Author/Authors :
Sutton، نويسنده , , Amanda E and Clardy، نويسنده , , Jon، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
A series of potentially selective inhibitors of dihydroorotate dehydrogenase (DHODH) were synthesized via iterative, chemoselective Suzuki cross-couplings utilizing biaryl chlorides as key intermediates.
Keywords :
dihydroorotate dehydrogenase , Suzuki cross-coupling , biaryl chloride
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters