Title of article :
Synthesis of a model compound of mappicine ketone based on sulfur-directed 5-exo selective aryl radical cyclization onto enamides
Author/Authors :
Ishibashi، نويسنده , , Hiroyuki S. Kato، نويسنده , , Issei and Takeda، نويسنده , , Yoshifumi and Tamura، نويسنده , , Osamu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
Enamides 10, upon treatment with Bu3SnH–AIBN, gave 5-exo aryl radical cyclization products 11, which were partially desulfurized to give 1-substituted dihydroisoindoles 7 and 12. This method was applied to the synthesis of a model compound 4 of mappicine ketone (1).
Keywords :
Enamides , radicals and radical reactions , antivirals , isoindoles , aryl halides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
