Title of article :
Diastereoselective synthesis of α-substituted β-amidophosphonates
Author/Authors :
Castelot-Deliencourt، Geraldine نويسنده , , Géraldine and Pannecoucke، نويسنده , , Xavier and Quirion، نويسنده , , Jean-Charles، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
A simple and general asymmetric synthesis of β-amidophosphonates is described. The method involves the highly selective addition (up to 95% d.e.) of diethyl phosphite to various chiral α,β-unsaturated carboxylic amides derived from chiral aminoalcohols.
Keywords :
phosphonic acids and derivatives , asymmetric synthesis , Michael addition
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
