Title of article :
1,3- versus 1,4-Asymmetric induction in Mukaiyama–Michael additions of optically active ketene acetals to 2-methylcyclopent-2-en-1-one: a remarkable inversion of facial selectivity
Author/Authors :
Gorobets، نويسنده , , Evgueni and Urbanczyk-Lipkowska، نويسنده , , Zofia and Stepanenko، نويسنده , , Viatcheslav and Wicha، نويسنده , , Jerzy، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
TrSbCl6-catalyzed addition of selected optically active ketene acetals to 2-methylcyclopent-2-en-1-one for steroid synthesis is described. Inversion of facial selectivity in 1,3- and 1,4-asymmetric induction was observed.
Keywords :
Sharpless dihydroxylation , Steroids , Asymmetric induction , Mukaiyama–Michael reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
