Author/Authors :
Roche، نويسنده , , Didier and Prasad، نويسنده , , Kapa and Repic، نويسنده , , Oljan and Blacklock، نويسنده , , Thomas J، نويسنده ,
Abstract :
A five-step stereoselective synthesis of both (2S,5S)- and (2S,5R)-2-amino-5-hydroxycaprolactam has been achieved via the aldol reaction of l-glutamic aldehyde 1 with nitromethane.