Title of article
Enantiospecific total synthesis of the enantiomer of the indole alkaloid affinisine
Author/Authors
Liu، نويسنده , , Xiaoxiang and Wang، نويسنده , , Tao and Xu، نويسنده , , Qingge and Ma، نويسنده , , Chunrong and Cook، نويسنده , , James M، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
6299
To page
6303
Abstract
The enantiomer of affinisine has been synthesized (from l-tryptophan) with 100% diastereoselectivity via the asymmetric Pictet–Spengler reaction coupled with a Pd0 (enolate mediated) coupling process. This enantiomer has also been converted into a key intermediate which provides a route to the enantiomers of both macroline and alstonerine following the previous work of LeQuesne.
Keywords
Pictet–Spengler reaction , enantiomer of affinisine , macroline , alstonerine
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1642227
Link To Document