Author/Authors :
Dudot، نويسنده , , Bruno and Chiaroni، نويسنده , , Angèle and Royer، نويسنده , , Jacques، نويسنده ,
Abstract :
A Yb(OTf)3-catalyzed Mannich-type reaction of the chiral non-racemic silyloxypyrrole 2 is described. The three-component (silyloxypyrrole, aldehyde and amine) reaction allowed the use of aromatic as well as aliphatic enolisable aldehydes. The erythro selectivity was proved by chemical correlation and X-ray analysis.
