Title of article :
A new straightforward synthesis of 2,3-aziridino-γ-lactones
Author/Authors :
Carole de Saint-Fuscien، نويسنده , , Carole and Tarrade، نويسنده , , Aurélie and Dauban، نويسنده , , Philippe and Dodd، نويسنده , , Robert H، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
A concise synthesis of 2,3-aziridino-γ-lactones starting from commercially available α,β-dihydroxy-γ-lactones is described. The strategy involves a Michael-type addition of benzylamine onto a key 2-(5H)-furanon-3-yl trifluoromethanesulfonate, followed by in situ cyclization to the aziridine without lactone-ring-opening.
Keywords :
aziridine , furanone , triflate , Michael-type addition
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
