Direct strand cleavage via furanyladenine formation in anaerobic photoirradiation of 5-bromouracil-containing oligonucleotides
Author/Authors :
Fujimoto، نويسنده , , Kenzo and Ikeda، نويسنده , , Yutaka and Saito، نويسنده , , Isao، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Pages :
5
From page :
6455
To page :
6459
Abstract :
The mechanism of direct strand cleavage induced by anaerobic irradiation of 5-bromouracil (BrU)-containing DNA was investigated. The formation of an oligonucleotide fragment containing 3′-furanyladenine end like 5 was observed as a major photoproduct for the direct strand breaks.
