Title of article
Zinc mediated Barbier type propargylation of cyclic imides
Author/Authors
Kim، نويسنده , , Sung Hoon and Han، نويسنده , , Eun-Hyoung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
6479
To page
6482
Abstract
Propargylations of cyclic imides such as N-benzylsuccinimide and N-methylsuccinimide were accomplished under mild Barbier type conditions using zinc metal, propargyl bromides and catalyst. The use of PbBr2 is essential to ensure the completion of the reaction to provided propargylated γ-hydroxylactams in high yields without the recovery of cyclic imides.
Keywords
Zinc , propargyl bromide , ?-hydroxylactam , Propargylation , cyclic imide , Barbier
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1642787
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